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Salbutamol

Presentation
  • 5 mg in 2.5 mL polyamp
  • pMDI (100 mcg per actuation)
Pharmacology

A synthetic beta adrenergic stimulant with primarily beta 2 effects

Actions:

  • Causes bronchodilatation
Metabolism

By the liver; excreted by the kidneys

  1. Respiratory distress with suspected bronchospasm:
    • asthma
    • severe allergic reactions
    • COPD
    • smoke inhalation
    • oleoresin capsicum spray exposure
  1. Nil of significance in the above indication
  1. Large doses of Salbutamol have been reported to cause intracellular metabolic acidosis
Route of administration
  • Nebulised
  • pMDI
  • Sinus tachycardia
  • Muscle tremor (common)
Special Notes

Salbutamol nebules / polyamps have a shelf life of one month after the wrapping is opened. The date of opening of the packaging should be recorded and the drug should be stored in an environment of < 30°C

Although infrequently used, Salbutamol by IV infusion may be required during interhospital transfers of some women in premature labour

The dose is to be prescribed and signed by the referring hospital medical officer

Nebulised effects:

Onset: 5 – 15 minutes
Peak: n/a
Duration: 15 – 50 minutes

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