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Dexamethasone

Presentation
  • 8 mg in 2 mL glass vial
Pharmacology

A corticosteroid secreted by the adrenal cortex

Actions:

  • Relieves inflammatory reactions
  • Provides immunosuppression
Metabolism

By the liver and other tissues; excreted predominantly by the kidneys

  1. Bronchospasm associated with acute respiratory distress not responsive to nebulised Salbutamol
  2. Moderate – severe croup
  3. Acute exacerbation of COPD
  4. Adult stridor (non-foreign body obstruction)
  1. Known hypersensitivity
  1. Solutions which are not clear or are contaminated should be discarded
Route of administration
  • IV (administered over 1 – 3 minutes)
  • IM
  • Oral
Special Notes

Does not contain an antimicrobial agent, therefore use solution immediately and
discard any residue.

IV Effects

Onset: 30 – 60 minutes
Peak: 2 hours
Duration: 36 – 72 hours

Quiz