Home Aspirin

Aspirin

Presentation
  • 300 mg chewable tablet
  • 300 mg soluble or water dispersible tablets
Pharmacology

An analgesic, antipyretic, anti-inflammatory and antiplatelet aggregation agent

Actions:

  • To minimise platelet aggregation and thrombus formation in order to retard the progression of coronary artery thrombosis in ACS
  • Inhibits synthesis of prostaglandins – anti-inflammatory actions
Metabolism

Converted to salicylate in the gut mucosa and liver; excreted mainly by the
kidneys

  1. Hypersensitivity to aspirin / salicylates
  2. Actively bleeding peptic ulcers
  3. Bleeding disorders
  4. Suspected dissecting aortic aneurysm
  5. Chest pain associated with psychostimulant OD if SBP >160 mmHg
  1. Peptic ulcer
  2. Asthma
  3. Patients on anticoagulants
Route of administration
  • Oral
  • Heartburn, nausea, gastrointestinal bleeding
  • Increased bleeding time
  • Hypersensitivity reactions
Special Notes

Aspirin is C/I for use in acute febrile illness in children and adolescents. The anti-platelet effects of Aspirin persist for the natural life of platelets.

Onset: n/a
Peak: n/a
Duration: 8 – 10 days

Quiz